While the state of Tennessee itself maintains sister-state relationships (such as with Yamanashi Prefecture in Japan), its major cities participate actively in the Sister Cities International program:
* **Nashville**: Sister cities include Belfast (Northern Ireland), Caen (France), Edmonton (Canada), Magdeburg (Germany), Mendoza (Argentina), Taiyuan (China), and Tamworth (Australia). * **Memphis**: Sister cities include Kanifing (The Gambia), Kaolack (Senegal), and Shoham (Israel). * **Chattanooga**: Sister cities include Hamm (Germany), Wuxi (China), and Tono (Japan). * **Knoxville**: Sister cities include Chełm (Poland), Chengdu (China), and Muroran (Japan).