While Calvert County was historically dominated by tobacco farming, modern agriculture in Lusby has transitioned to smaller-scale operations. Today, local farms focus on field crops such as corn, soybeans, and wheat.
Agritourism has become increasingly popular, with local farms offering produce stands, seasonal festivals, and community-supported agriculture (CSA) programs. Furthermore, aquaculture—specifically the farming of oysters and the harvesting of blue crabs—remains an important cultural and economic activity in the waterways surrounding the Lusby peninsula.